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The directive to public schools says transgender students should use the gender bathroom they identify with. Renee Montagne talks to Jayne Ellspermann, principal of West Port High School in Florida.

David Mandel, the Emmy-nominated writer, director and executive producer of the HBO series Veep, discusses the current season of the show, his work on SNL and the 2016 presidential election.

Okay, so Lady Gaga and The Black Eyed Peas are atop pop charts everywhere. But Talk of the Nation wants to know: What else is popular where you live? And how did you hear about it? A popular musician, a Kenyan radio DJ and an international music expert discuss.

For the first time, Scots will be able to vote on whether they want to remain part of the United Kingdom or strike out on their own. So far, polls suggest most favor unity over independence.

Negotiations continued between the White House and House Speaker John Boehner on Tuesday to avoid the fiscal cliff. Earlier in the day, Boehner prepared his fellow House Republicans for the likelihood that taxes will have to rise on top earners. He's also now talking about a "plan B" if talks fail to come to a deal. Tamara Keith joins Melissa Block from Capitol Hill.

President Obama is promoting new initiatives to improve education for Native American students. Ahniwake Rose, executive director of the National Indian Education Association, has the details.

President Obama's re-election campaign has tried to master the recipe for viral videos with its new 17-minute offering, The Road We've Traveled. This biographical film is directly related to the kinds of movies that campaigns used to make for a party's nominating convention. Its goal is to ultimately reach undecided independent voters.

A series of tornadoes ripped across north Texas on Wednesday night, killing six people and injuring dozens of others. The strongest tornado hit the city of Granbury with winds approaching 200 mph. Rescue crews were going door-to-door on Thursday searching for survivors.

When we talk, we focus on the "content" words — the ones that convey information. But the tiny words that tie our sentences together have a lot to say about power and relationships.

For its latest anti-tobacco campaign, the Food and Drug Administration wants to harness hip-hop swagger to reach minority teens — who disproportionately suffer the consequences of smoking.

Read an exclusive excerpt of Scott Lynch's long-awaited new Gentleman Bastard book, The Republic of Thieves. In this installment, dashing thieves Locke and Jean are hired to help fix an election in the city of Karthain. The twist? The opposition has hired their own dirty trickster — Locke's long-lost love, Sabetha.

American officials tell NPR that Syria's preparations are more extensive than previously reported. The U.S. and NATO are preparing for ways to address the chemical weapons threat.