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"I wish President Obama had succeeded because I want America to succeed," the Republican presidential nominee plans to tell the nation tonight. But instead, he will say, "hope and change" have turned to disappointment.

The protest organizers are calling for a boycott of work, school and shopping to protest Trump administration policies and what activists describe as a billionaire takeover of government.

The antidepressant Prozac selectively targets the chemical serotonin. When the drug was introduced in the 1980s, it helped solidify the idea in many minds that depression was the result of a chemical imbalance. But the real story is far more complicated.

Other banks did make progress erasing $1.3 billion of mortgage principle through loan modifications.

The twin ports of Los Angeles and Long Beach have some of the dirtiest air, thanks to thousands of old diesel cargo trucks that pass through each day. But new emissions standards just went into effect banning those old trucks. Neighboring communities are breathing a sigh of relief, but the restrictions are taking a toll on low-wage truck drivers.

On today's Your Call we’ll have a conversation with Sean Strub, author of Body Count: A Memoir of Politics, Sex, AIDS, and Survival. What can we learn…

The violin takes center stage in an exhibit at the Library of Congress. The instrument's popularity has cut across economic, racial and regional lines and helped drive new forms of American music, from blues and jazz to bluegrass and swing.

At the 2012 Great American Beer Festival, 2,700 different beers were served up by some of the best breweries in the United States. For the event's 49,000 attendees, the festival is a chance to try new and unique beers; for the brewers, it's a way to make a name for themselves.

Coffee runs through the veins of Latin America. This week on Alt.Latino, hear some of the songs the drink has inspired.

Bank of America says it expects to eliminate up to 35,000 jobs over the next three years. It says it won't know the final number until early next year, but the cuts will affect workers from both Bank of America and Merrill Lynch. Bank of America agreed to buy the investment firm in September.

In an interview with Terry Gross, taped in front of a live audience in New York City, the Daily Show host deconstructs his upcoming "Rally to Restore Sanity" on the National Mall and explains how The Daily Show comes up with material.

Marcella Hazan is credited with introducing Americans to true Italian cooking. But she began her career teaching science — and didn't have much of an interest in food.